Name: Cyanocobalamin
Synonyms: Cyano-5,6-dimethylbenzimidazole-cobalamin; Vitamin B12
Molecular Formula: C63H88CoN14O14P
Molecular Weight: 1355.38
CAS Number: 68-19-9
EINECS: 200-680-0
Cyanocobalamin is an especially common vitamin of the B12 vitamin family.
Cyanocobalamin is the most famous vitamin of the family, because it is chemically the most air-stable, and
Cyanocobalamin is the easiest to crystallize and therefore easiest to purify after it is produced by bacterial fermentation. The cyanide is added to the molecule by activated charcoal columns in purification. Thus, the use of this form of B12 is the most wide-spread. This fact has caused some people (usually from reading labels on packages and vitamin supplements, in which
vitamin B12 is almost always listed last, since ingredients by law are listed in order of weight percentage), to infer that the correct chemical name of
vitamin B12 actually is cyanocobalamin. In fact,
vitamin B12 is the name for a whole class of chemicals with B12 activity, and cyanocobalamin is only one of these.
Cyanocobalamin usually does not even occur in nature, and is not one of the forms of the vitamin which is directly used in the human body (or that of any other animal). However, animals and humans can convert it to active (cofactor) forms of the vitamin, such as methylcobalamin.
Specification
| Product name |
Vitamin B12 |
| Test Items |
Specifications (USP28) |
| Appearance |
Dark red crystalline powder |
| Identification |
Accord with the test |
| Assay |
96.0-102.0% |
| Loss on drying |
12.0% Max |
| Related substances |
3% Max |
| Ratio absorbances |
A361nm/A278nm: 1.70-1.90 A361nm/A550nm: 3.15-3.45 |
| Pseudo cyanocobalmin |
Accord with the test |
Packing: Carton/cardboard barrel, with PE bag, net weight 25KG.
Storage: Stored in a dry and cool place, keep away from strong light and heat.
Shelf life: Two years when stored properly in a well-closed container.
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